Cake Mix Blueberry Muffins
Updated May 02, 2026
These Cake Mix Blueberry Muffins are made with a box of cake mix and a quick homemade streusel topping. Bakery style muffins made in a fraction of the time!
Cake Mix Blueberry Muffins
Say hello to the easiest blueberry muffins you will ever make!
These bakery style blueberry muffins will have your house smelling amazing.
Cake mix recipes are one of our favorite time saving hacks for making delicious homemade treats in a fraction of the time.
These easy blueberry muffins are incredibly light and fluffy and melt in your mouth delicious.
“I tried the recipe and baked the best, moist, delicious giant blueberry muffins that I have ever baked. I have tried to buy muffins like these, but never found them. I will continue to use this recipe. Thanks so much!” -reader review
Ingredients needed to make blueberry muffins
- Vanilla cake mix: you can also use white or yellow cake mix.
- Fresh blueberries: I do not recommend frozen blueberries for this recipe.
- Eggs
- Lemon zest: Don’t skip this! It gives the muffins such a delicious burst of lemon-y flavor.
- Oil: any neutral cooking oil like olive oil or vegetable oil.
- Milk
- Butter, flour & brown sugar: for the easy streusel topping.
How to make muffins from cake mix
Step 1: Grate the lemon zest. Add the eggs, milk, lemon zest, and olive oil to a bowl. Whisk the wet ingredients until completely combined.
Step 2: Open up a box of vanilla cake mix and place it in a bowl. Mix the wet ingredients into the cake mix, stirring until just combined.
Step 3: Rinse and pat the blueberries completely dry. Fold the blueberries into the cake mix muffin batter gently with a rubber spatula.
Step 4: Make the streusel topping for the blueberry muffins. Combine the melted butter, brown sugar, and flour in a bowl. Stir it up to combine the ingredients.
Step 5: Line a muffin tin with muffin liners. Distribute the blueberry muffin batter evenly into the muffin tins.
Step 6: Distribute the streusel topping over the muffin batter.
Step 7: Bake the cake mix blueberry muffins at 350 degrees for 23-28 minutes, or until a toothpick inserted comes out clean.
You kitchen will be smelling like a bakery.
These muffins not only taste incredible but no one will guess they are made from cake mix: our little secret!
While I love making homemade sour cream blueberry muffins, these are a great muffin to make when I need a shortcut!
Easy Cake Mix Blueberry Muffins
Ingredients
- 1 cup fresh blueberries, rinsed and patted completely dry
- 15 oz box vanilla cake mix
- 3 eggs, beaten
- 1 teaspoon fresh lemon zest
- ½ cup milk
- ⅓ cup oil, olive oil or vegetable oil
For the streusel topping
- ⅓ cup flour
- ⅓ cup brown sugar
- 2 tablespoons unsalted butter, melted
Instructions
- Add the vanilla cake mix to a large mixing bowl.
- In a separate bowl, whisk together the eggs, milk, lemon zest, and oil.
- Stir the wet ingredients into the cake mix until just combined using a rubber spatula.
- Fold in the fresh blueberries.
- To make the streusel, combine the flour, brown sugar, and melted butter in a small bowl until combined.
- Line a muffin tin with 12 liners.
- Distribute the muffin batter into the muffin cups. Top the batter with the streusel topping.
- Bake the blueberry muffins at 350 degrees for 23-28 minutes or until a toothpick inserted comes out clean.
Nutrition
Can I freeze some after I make them
Can you use frozen blueberries?
I just made these muffins, and they are delicious! I almost skipped the streusel topping. So glad I didn’t! I used a Golden Butter cake mix instead of vanilla as that is what I had in the house. I might add lemon juice to make it a bit more lemony.
Can I use frozen blueberries?
I would not, as they will be more watery and may result in a different texture of the muffin.
@Mar,
I always use frozen blueberries when making muffins. They are not too wet, nor do they require any changes to the essential ingredients. Defrost first, pat dry and then fold in just as you would fresh.
Can yellow cake mix be substituted for the white?
Yes!
What can I use instead of olive oil?
Vegetable oil will also work
@Joy Shull,
I used light blue plate mayo because I didn’t have oil nor butter. They turned out great.
How would you substitute cranberries?
@Natty, I chopped Frozen cranberries up in my food chopper and substituted for blueberries. Turned out fine!
I made these blueberry muffins and they were a great hit. I had been buying Little bites muffins and these are bigger and healthier.
Can I use applesauce instead of the oil?
I have not tested it in this recipe specifically. Usually it’s an ok sub, let me know if you try it!
Hi Joy. I tried the recipe and baked the best, moist, delicious giant blueberry muffins that I have ever baked. I have tried to buy muffins like these, but never found them. I will continue to use this recipe. Thanks so much! Constance Jones
I’m so happy you enjoyed the recipe!